https://www.againstmalaria.com/

If you're looking to help fight malaria, check out the Against Malaria Foundation. They're super transparent and get stuff done. 100% of public donations buy long-lasting insecticidal nets that keep folks safe from malaria. They even check up on things after giving out the nets to make sure they're doing their job. By supporting them, you're helping to kick malaria to the curb for good!

https://www.alexslemonade.org/

Alex’s Lemonade Stand is a foundation that has raised more than $250 million for Childhood cancer and funded over 1,000 research projects.

Alex was a little girl that was diagnosed with cancer when she was 1 year old, one day when Alex was in the hospital she told her parents that she wanted to have a lemonade stand. When asked what she wanted to buy with the money, she told her parents she didn’t want to spend the money she wanted to give the money to doctors so they could help more kids. Alex, unfortunately, passed away, but her mission lived on through the Alex’s Lemonade Stand Foundation.

Not only does Alex’s Lemonade Stand Foundation help provide grants to study childhood cancers, but they also provide support to families with children fighting childhood cancers. Their Travel For Care Program helps to offset travel costs for families who need to travel to get their child the most care. They also have a SuperSibs program that provides support for siblings of children who are fighting cancer.

https://www.cmtausa.org/

The CMTA has a 4 (out of 4) star rating on Charity Navigator and they have been instrumental in funding pre-clinical research and treatment development, as well as funding camps for kids with CMTA who have mobility and dexterity challenges (Camp Footprint!).

A lot of their investment and advocacy has already paid off as one of the CMT 1A treatments that they had invested in was acquired by Novartis in July! I have been working really closely with a neurologist/researchers from University of Rochester in NY and one at the Gene Institue of Cyprus in Europe to develop a natural history study for CMT 4C to show how the disease progresses over time, which will be absolutely essential for getting any biotech or pharma companies interested in treating CMT 4C (since they need "control" data to be able to prove that a treatment is working). They are presenting their proposal to the CMTA advisory board next month for approval and their goal is to have neurologists from the CMTA Centers of Excellence at UPenn, U of Iowa, and U of Rochester participate (with 2 locations in Europe, also).

All this to say, I am extremely pleased with the work that they do and I have watched firsthand the leaps and bounds they have made over the past several years to get CMT from the point of very little information to the point where they have identified dozens of genes that cause the disease, and have several promising gene therapies in development, and have multiple treatments for CMT 1A in human trials.

https://comfortcases.org/

Comfort Cases provides children entering the foster care system backpacks that are filled with comfort and personal items. When most children enter the foster care system they are given a garbage bag to carry their belongings and comfort care is working to ensure that children entering the foster system are provided with the items they need for their first few days in the foster system.

https://www.chadtough.org/about-us/

In the fight for a DIPG/DMG cure, we help patients and families by funding game-changing research and providing navigation throughout their journey.

We see a world where kids diagnosed with DIPG/DMG can have bright futures and can live out their dreams.

https://www.jbcfund.org/

The JBC PANS & PANDAS Foundation provides emotional and practical support to help families like yours start on a path to healing.

PANS (Pediatric Acute-Onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Syndrome Associated with Streptococcus) occur when the body’s immune system mistakenly attacks healthy cells following an infection (e.g., strep throat), leading to brain inflammation. This misdirected immune response results in an acute onset of neuropsychiatric symptoms ranging from severe anxiety, aggression, and irritability to motor and sensory abnormalities. Symptoms are often very sudden in onset and can be alarming. Many parents describe watching their son or daughter transform into a child they do not recognize.

https://kitchensforgood.org/about/

Kitchens for Good is a sustainability-oriented San Diego nonprofit dedicated to making a positive impact on our economy, society, and environment.

The heartbeat of the organization is our tuition-free Apprenticeship Programs in Culinary, Baking, and Food Service professions that help individuals facing barriers to employment become work ready, be placed in quality jobs, and start a career in San Diego’s robust Hospitality industry.

At Kitchens for Good we are dedicated to helping people take the next step forward in their lives.

Our Apprentices, many of whom have been impacted by histories of trauma, and have faced barriers to employment, gain the technical and life skills they need to launch meaningful careers in the hospitality industry. Through our California state-certified Apprenticeship programs, our Apprentices are able to secure well-paying jobs, gain confidence, continue to grow, and positively contribute to their communities.

https://pandasnetwork.org/

Pandas network is more about awareness and making people aware this is a real problem affecting kids. The JBC foundation actually spends most of its funds directly helping people in need who have been diagnosed with it as much of the care is not covered by standard insurance or is in trial phases currently so it is very expensive to treat.

Unfortunately, it is a newer neurological issue that affects 1 in 200 kids but is very underdiagnosed as it displays in each kid uniquely and usually as another problem like OCD, verbal or motor tics, Anxiety, Emotional instability, hallucinations, Urinary problems, and joint pain. These can have a huge effect on kids’ social and school performance and can even cause deterioration in both which can be detrimental to younger kids.

https://www.splcenter.org/about-us/impact-report

2022 was the Southern Poverty Law Center’s 51st year fighting for a multiracial, inclusive democracy. While our opponents grow more vocal, the SPLC continues evolving and expanding to meet their hate with our collective resolve. Your partnership helps keep us strong. As you’ll see in our 2022 Impact Report below, we leveraged our legal, advocacy, education and community partnership efforts to pursue our four main goals: Strengthening Democracy, Fighting White Supremacy, Eradicating Poverty and Reducing Incarceration. These are bold areas of impact for the bold future we envision: a world in which everyone can thrive.

https://thewaterproject.org/about_us

The Water Project, Inc. is a 501(c)(3) non-profit organization unlocking human potential by providing reliable water projects to communities in sub-Saharan Africa who suffer needlessly from a lack of access to clean water and proper sanitation.

Since 2006, we have been helping communities gain access to clean, safe water by providing training, expertise and financial support for water project construction through our staff and implementing partners.